Past Research Support
Funding Agency: Washington University/Monsanto
Period: 07/01/93 – 06/30/94
Grant Title: Regulation of Matrix Metalloproteinase Activity in Human and
Experimental Abdominal Aortic Aneurysms
Grant Number: New Investigator Award
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $10,000
Annual Direct Costs: $10,000
Percent of Effort: 10
Funding Agency: National Institutes of Health (NIGMS)
Period: 07/01/93 – 06/30/96
Grant Title: Institutional National Research Service Award
Trauma and Burns Research Training Grant
Grant Number: 5 T32 GM07602
Principal Investigator: Timothy J. Buchman, Ph.D., M.D.
Research Trainee: Dennis R. Holmes, M.D.
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $60,000
Annual Direct Costs: $30,000
Percent of Effort: 0
Funding Agency: Washington University Institute for Minimally Invasive Surgery
and Ethicon, Inc.
Period: 07/01/94 – 06/30/95
Grant Title: Laparoscopic-Assisted Aortic Reconstruction in a Porcine Model
Grant Number: Research Grant
Principal Investigator: Robert W. Thompson, M.D.
Co-Investigator: Brian G. Rubin, M.D.
Total Direct Costs: $5,000
Annual Direct Costs: $5,000
Percent of Effort: 5
Funding Agency: American College of Surgeons
Period: 07/01/94 – 06/30/96
Grant Title: Pericellular Proteolysis in Aortic Aneurysm Disease
Grant Number: Faculty Fellowship
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $60,000
Annual Direct Costs: $30,000
Percent of Effort: 70
Funding Agency: American Heart Association, Missouri Affiliate
Period: 07/01/95 – 06/30/97
Grant Title: Pharmacotherapy of Abdominal Aortic Aneurysms
Grant Number: Research Grant-in-Aid
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $50,000
Annual Direct Costs: $25,000
Percent of Effort: 20
Funding Agency: National Institutes of Health (NHLBI)
Period: 07/01/96 – 06/30/98
Grant Title: Institutional National Research Service Award
Basic Science Research Training in Cardiopulmonary Surgery
Grant Number: 5 T32 HL07776
Principal Investigator: John P. Boineau, M.D.
Research Trainee: John A. Curci, M.D.
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $60,000
Annual Direct Costs: $30,000
Percent of Effort: 0
Funding Agency: Pacific Vascular Research Foundation
Period: 07/01/96 – 06/30/99
Grant Title: Medial Degeneration in Abdominal Aortic Aneurysms
Grant Number: Edwin J. Wylie Scholar Award in Academic Vascular Surgery
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $150,000
Annual Direct Costs: $50,000
Percent of Effort: 10
Funding Agency: National Institutes of Health (NHLBI)
Period: 08/01/96 – 07/31/00
Grant Title: Molecular Mechanisms of Aneurysmal Degeneration
Grant Number: 1 R29 HL56701
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $280,000
Annual Direct Costs: $80,000
Percent of Effort: 50
Funding Agency: Roche Biosciences, Inc. (Palo Alto, CA)
Period: 11/01/97 – 12/31/97
Grant Title: Efficacy of Hydroxamic Acid-Based MMP Inhibitors on
Experimental Abdominal Aortic Aneurysms
Grant Number: Pilot Study
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $7,000
Annual Direct Costs: $7,000
Percent of Effort: 5
Funding Agency: National Institutes of Health (NIA)
Period: 07/01/97 – 06/30/99
Grant Title: Smooth Muscle Cell Senescence in Aortic Aneurysms
Grant Number: 1 R03 AG14805
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $50,000
Annual Direct Costs: $25,000
Percent of Effort: 20
Funding Agency: The Lifeline Foundation
Period: 05/01/98 – 08/31/98
Grant Title: The Effects of Doxycycline on mRNA Regulation of Repair Proteins in
a Rat Model of Abdominal Aortic Aneurysms
Grant Number: Student Research Fellowship
Research Trainee: Mark D. Huffman, B.S.
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $2,000
Annual Direct Costs: $2,000
Percent of Effort: 0
Funding Agency: Novartis, Inc. (Summit, NJ)
Period: 10/15/98 – 12/31/98
Grant Title: Effect of a Dual MMP/TACE Inhibitor on the Development and Growth
Of Experimental Abdominal Aortic Aneurysms
Grant Number: Research Grant
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $10,000
Annual Direct Costs: $10,000
Percent of Effort: 5
Funding Agency: National Institutes of Health (NHLBI)
Period: 07/01/98 – 06/30/99
Grant Title: Institutional National Research Service Award
Cardiovascular Pharmacology Training Grant
Grant Number: 5 T32 HL07275
Principal Investigator: Jeanne M. Nerbonne, Ph.D.
Research Trainee: John A. Curci, M.D.
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $30,000
Annual Direct Costs: $30,000
Percent of Effort: 0
Funding Agency: Parke-Davis Pharmaceutical Research, Warner-Lambert Company
Period: 11/01/98 – 10/31/99
Grant Title: Evaluation of CI-1026 in an Elastase-Induced Rat Model of Abdominal
Aortic Aneurysm
Grant Number: Research Grant
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $75,000
Annual Direct Costs: $75,000
Percent of Effort: 5
Funding Agency: The Lifeline Foundation
Period: 04/01/99 – 07/31/99
Grant Title: Cytokine Regulation of Collagenase-3 Expression in Vascular Smooth
Muscle Cells Derived from Abdominal Aortic Aneurysms
Grant Number: Student Research Fellowship
Research Trainee: Sarah J. VanVickle
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $2,000
Annual Direct Costs: $2,000
Percent of Effort: 0
Funding Agency: National Institutes of Health (NHLBI)
Period: 07/01/99 – 06/30/01
Grant Title: Individual National Research Service Award
The Role of Collagenases in Human Abdominal Aortic Aneurysms
Grant Number: 1 F32 HL10283
Principal Investigator: Jason K. Lee, M.D.
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $70,000
Annual Direct Costs: $35,000
Percent of Effort: 0
Funding Agency: American Heart Association, Heartland Affiliate
Period: 07/01/99 – 06/30/01
Grant Title: Plasma MMP Levels in Patients with Aortic Aneurysms: Effects of
Disease Progression and Doxycycline Treatment
Grant Number: Research Grant-in-Aid 9951317Z
Principal Investigator: Robert W. Thompson, M.D.
Co-Investigator: David M. Hovsepian, M.D.
Total Direct Costs: $70,000
Annual Direct Costs: $35,000
Percent of Effort: 10
Funding Agency: National Institutes of Health (NHLBI)
Period: 10/01/99 – 09/30/03 (no-cost extension to 09/30/04)
Grant Title: Molecular Pathophysiology of Abdominal Aortic Aneurysms:
Regulated Expression of Collagenases in AAA
Grant Number: 1 R01 HL64332
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $600,000
Annual Direct Costs: $150,000
Percent of Effort: 20
Funding Agency: National Institutes of Health (NHLBI)
Period: 10/01/99 – 09/30/03 (no-cost extension to 09/30/04)
Grant Title: Molecular Pathophysiology of Abdominal Aortic Aneurysms:
Aneurysm Research Core
Grant Number: 1 R01 HL64333
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $200,000
Annual Direct Costs: $50,000
Percent of Effort: 5
Funding Agency: The Lifeline Foundation
Period: 04/01/00 – 07/31/00
Grant Title: Role of Elastin Degradation Peptides in the Development of Experimental
Abdominal Aortic Aneurysms
Grant Number: Student Research Fellowship
Research Trainee: Scott J. Ziporin, M.A.
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $3,000
Annual Direct Costs: $3,000
Percent of Effort: 0
Funding Agency: National Institutes of Health (NHLBI)
Period: 08/01/00 – 07/31/05
Grant Title: Molecular Mechanisms of Aneurysmal Degeneration
Grant Number: 2 R01 HL56701
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $800,000
Annual Direct Costs: $200,000
Percent of Effort: 20
Funding Agency: American Heart Association, Heartland Affiliate
Period: 07/01/01 – 06/30/03
Grant Title: Immunomodulatory Mechanisms in Abdominal Aortic Aneurysms
Grant Number: Beginning Grant-in-Aid
Principal Investigator: Patrick J. Geraghty, M.D.
Collaborating Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $110,000
Annual Direct Costs: $55,000
Percent of Effort: 5
Funding Agency: Medtronic AVE, Inc. (Santa Rosa, CA)
Period: 10/15/03 – 10/14/04
Grant Title: Suppression of Experimental Abdominal Aortic Aneurysms by Local Administration of Doxycycline
Grant Number: Investigator-Initiated, Industry-Supported Research Grant
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $100,000
Annual Direct Costs: $100,000
Percent of Effort: 5
Funding Agency: National Institutes of Health (NHLBI)
Period: 07/01/03 – 06/30/05
Grant Title: Ruth L. Kirschstein Individual National Research Service Award
Role of Angiotensin Receptors in Experimental AAA
Grant Number: 1 F32 HL074520
Principal Investigator: Jack R. Oak, M.D.
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $93,000
Annual Direct Costs: $45,000
Percent of Effort: 0
Funding Agency: National Institutes of Health (NHLBI)
Period: 07/01/04 – 06/30/05
Grant Title: Ruth L. Kirschstein Individual National Research Service Award
Suppressive Cellular Immunity in Experimental AAA
Grant Number: 1 F32 HL078133
Principal Investigator: Celine Buckley, M.D.
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $99,600
Annual Direct Costs: $99,600
Percent of Effort: 0
Funding Agency: National Institutes of Health (NHLBI)
Period: 04/18/05 – 03/31/10
Grant Title: Mentored Clinical Scientist Research Career Development Award
Matrix Metalloproteinases in Thoracic Aortic Dissection
Grant Number: 1 K08 HL080085
Principal Investigator: Scott A. LeMaire, M.D. (Baylor College of Medicine, Houston)
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $500,000 (to Baylor College of Medicine, Houston)
Annual Direct Costs: $100,000 (to Baylor College of Medicine, Houston)
Percent of Effort: 0
Funding Agency: Cordis Corporation/Johnson&Johnson (Piscataway, NJ)
Period: 07/01/05 – 06/30/06
Grant Title: Suppression of Experimental Abdominal Aortic Aneurysms by Local Administration of Sirolimus
Grant Number: Investigator-Initiated, Industry-Supported Research Grant
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $50,000
Annual Direct Costs: $50,000
Percent of Effort: 2
Funding Agency: National Institutes of Health (NHLBI)
Period: 08/01/05 – 07/31/10 (no-cost extension to 07/31/12)
Grant Title: Molecular Mechanisms of Aneurysmal Degeneration
Grant Number: 3 R01 HL56701
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $1,125,000
Annual Direct Costs: $225,000
Percent of Effort: 25
Funding Agency: National Institutes of Health (NHLBI)
Period: 04/01/06 – 03/31/11 (no-cost extension to 03/31/12)
Grant Title: SCCOR in Metabolic Syndrome and Vascular Disease
Core C: Vascular Surgery and Histopathology Laboratory
Grant Number: 1 P50 HL083762
Principal Investigator: Clay F. Semenkovich, MD
Project Leader: Core C: Gregorio A. Sicard, MD, PI; Robert W. Thompson, MD, Co-PI
Total Direct Costs: $750,000
Annual Direct Costs: $150,000
Percent of Effort: 5
Funding Agency: National Institutes of Health (NHLBI)
Period: 04/01/06 – 03/31/11 (no-cost extension to 03/31/12)
Grant Title: SCCOR in Metabolic Syndrome and Vascular Disease
Project 2: Metabolic Syndrome and Pathobiology of Aortic Aneurysms
Grant Number: 1 P50 HL083762
Principal Investigator: Clay F. Semenkovich, MD
Project Leader: Project 2: Robert W. Thompson, MD, PI
Total Direct Costs: $1,500,000
Annual Direct Costs: $300,000
Percent of Effort: 20
Funding Agency: National Institutes of Health (NHLBI)
Period: 07/01/07 – 06/30/12
Grant Title: Mentored Clinical Scientist Research Career Development Award
Vascular Smooth Muscle Cells and Elastolysis in Abdominal Aortic Aneurysms
Grant Number: 1 K08 HL084004
Principal Investigator: John A. Curci, M.D.
Research Mentor: Robert W. Thompson, M.D.
Total Direct Costs: $500,000
Annual Direct Costs: $100,000
Percent of Effort: 0
Funding Agency: National Institutes of Health (NCRR)
Period: 09/17/07 – 05/31/12
Grant Title: Washington University Institute of Clinical and Translational Sciences;
Sub-Project: Development of Novel Clinical & Translational Methodologies, Pilot & Collaborative Translational & Clinical Studies
Grant Number: 1 UL1 RR024992
Principal Investigator: Bradley Evanoff, MD, MPH
Project Leader: Robert W. Thompson, MD, Director Novel Methodologies and Pilot Studies Program (sub-project)
Total Direct Costs: $1,580,000 (sub-project only)
Annual Direct Costs: $316,065 (sub-project only)
Percent of Effort: 5
Funding Agency: National Institutes of Health (NHLBI)
Period: 08/01/10 – 07/30/15
Grant Title: Washington University Cardiovascular Program of Excellence in Nanotechnology; Project 4: Atherosclerosis and Aortic Aneurysm Disease
Grant Number: 268201000046C-0-0-1 (NIH Contract, TAS 75 0872)
Principal Investigator: Michael Welch, MD
Project Leader: Pamela Woodward, MD (sub-project);
Robert W. Thompson, MD, Collaborating Investigator
Annual Direct Costs: $17,689,000
Percent of Effort: 5
Funding Agency: Department of Veterans Affairs (VA)
Period: 10/01/12 – 09/30/17
Grant Title: Mentored Research Career Development Award (CDA)-2
Role of Inflammation in the Pathobiology of Abdominal Aortic Aneurysm
Grant Number: CARA-028-11F; 4098
Principal Investigator: Kathleen G. Raman, M.D.
Research Co-Mentor: Jeffrey F. Moley, M.D.
Research Co-Mentor: Robert W. Thompson, M.D.
Research Co-Mentor: Anne Marie Schmidt, M.D.
Total Direct Costs: $330,000
Annual Direct Costs: $60,000
Percent of Effort: 0
Funding Agency: National Institutes of Health (NIA)
Period: 08/01/13 – 07/31/14
Grant Title: Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial
Grant Number: 5R01 AG03712002
Principal Investigator: Robert W. Thompson, M.D.
Principal Investigator: Robert W. Thompson, M.D.
Total Direct Costs: $50,000
Annual Direct Costs: $50,000
Percent of Effort: 8
Funding Agency: Barnes-Jewish Hospital Foundation
Period: 07/01/12 – 06/30/25
Grant Title: Center for Thoracic Outlet Syndrome
Grant Number: BJHF Designated Fund 678733
Principal Investigator: Robert W. Thompson, M.D.
Annual Direct Costs: $25,000
Percent of Effort: 0
This philanthropy-derived fund provides support for clinical research studies conducted in the Washington University Center for Thoracic Outlet Syndrome at Barnes-Jewish Hospital, under the direction of Dr. Thompson. Salary support is provided for a clinical research assistant and database maintenance. Resources available and needed are reviewed and provided on an annual basis.
